The Rearrangement of cis-2-en-4:6-diyn-oic Acids to alphabeta-Unsaturated gamma-Lactones.

Palladium-catalyzed carbonylation of 2-(propargyl)allyl phosphates leading to highly unsaturated gamma-lactones.

Novel inducers of BECN1-independent autophagy: cis-unsaturated fatty acids.

The induction of autophagy usually requires the activation of PIK3C3/VPS34 (phosphatidylinositol 3-kinase, catalytic subunit type 3) within a multiprotein complex that contains BECN1 (Beclin 1, autophagy related). PIK3C3 catalyzes the conversion of phosphatidylinositol into phosphatidylinositol 3-phosphate (PtdIns3P). PtdIns3P associates with growing phagophores, which recruit components of the...

Inhibition of platelet function by cis-unsaturated fatty acids.

The uptake of free fatty acids has previously been shown to affect the capping of lymphocytes, and there is evidence that different types of fatty acids may partition into separate lipid domains in cell surface membranes. In studies of gel-filtered human platelets, we found that cis-unsaturated fatty acids (1-35 microM) inhibited platelet shape change, aggregation, and secretion of 5-hydroxytry...

Autoxidation of the fatty acids. 3. The oily products from elaidic and oleic acids. The formation of monoacyl derivatives of dihydroxystearic acid and of alphabeta-unsaturated keto acids.

In Part 1 (Ellis, 1932) it was shown that finely dispersed elaidic and oleic acids, when exposed to oxygen at temperatures of about 650, showed an uptake of over 20% by weight in a few hours. About one-fifth of this oxygen was evolved as carbon dioxide and an appreciable but uncertain amount of water vapour was also given off. In Part 2 (Ellis, 1936) it was shown that the main crystalline produ...

LINEAR ALIPHATIC UNSATURATED POLYESTERS BASED ON CIS -2- BUTENE -1,4-DIOL: SYNTHESIS AND CHARACTERIZATION

A new homologous series of linear aliphatic polyesters, such as poly (cis-2- butenylene carboxylate)S, PBms (m is the number of methylene groups in the acid component, m=2-8 have been synthesized by direct polyesterification reactions in anisole, as solvent. FT-IR, 400 MHz H- NMR, C-NMR and elemental analysis were used to establish the structure of polyesters. Molecular weight distributi...